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Physical interaction with Ephrin B1 promotes CXCR4 intracellular localization and oncogenic potential

Alessandro Rabbito et al.
HAL (France) · Papers
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cancerg-protein-coupled-receptorsignal-transduction
Chemokine receptor 4 (CXCR4) is a member of the chemokine receptor family, exclusively activated by the chemokine CXCL12. While CXCR4 regulates numerous physiological processes associated with cell migration and embryogenesis, its overexpression has been involved in various cancer types. Studies sug
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