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Endothelial Arf6 sustains electrical signaling and cerebral blood flow in mice through PIP2-dependent activation of Kir2.1 channels
Brain capillaries sense neural activity and direct blood flow to active regions—a process termed neurovascular coupling that underlies activity-dependent increases in local perfusion (functional hyperemia). A key contributor to functional hyperemic responses is the capillary endothelial cell (cEC) i
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