Jurnal Surya Medika (JSM)
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Optimasi Formulasi Tablet Lepas Lambat Ekstrak Seledri (Apium graveolens L.) Menggunakan Polimer Xanthan Gum dan Lubrikan Magnesium Stearat dengan Metode Simplex Lattice Design (SLD): Optimization of Celery Extract (Apium graveolens L.) Sustained Release Tablet Formulation Using Xanthan Gum Polymer and Magnesium Stearate Lubricant with Simplex Lattice Design (SLD) Method
Antihypertensive drugs undergo first-pass metabolism and therefore have low oral bioavailability. It causes an increase in the frequency of drug use and concentration fluctuations that affect patient comfort. The sustained release tablet formulation was chosen because it can deliver the active subst
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