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Stat3 signalling via the il-6ST/GP130 cytokine receptor promotes epithelial integrity and intestinal barrier function during DSS-induced colitis
The intestinal epithelium provides a barrier against commensal and pathogenic microorganisms. Barrier dysfunction promotes chronic inflammation, which can drive the pathogenesis of inflammatory bowel disease (IBD) and colorectal cancer (CRC). Although the Signal Transducer and Activator of Transcrip
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