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A Phase 2 Study of CRD-4730 in CPVT

Cardurion Pharmaceuticals, Inc. · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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arrhythmiacardiovascularventricular-tachycardia
This is a Phase 2, multicenter, double-blind, sponsor blinded, placebo-controlled, repeat-dose clinical study of CRD-4730 to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of CRD-4730 to participants with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT). Participants with CPVT will complete a 3-period, randomized 3-sequence study. Each participant will be randomized to one of the 3 sequences in which they will receive 2 different doses of CRD-4730 and 1 dose of matching placebo.
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