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On the interpretation of the kinetics of ligand-receptor binding

Colquhoun, David et al.
arXiv (All) · Papers
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quantitative-methods
When the rates of ligand binding are measured by methods such as surface plasmon resonance, it is common practice to use the observed rate constants for the onset and offset of binding to estimate an equilibrium constant for ligand binding. If this agrees with the equilibrium constant found as the E
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