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Decoding Extrahepatic Targeting of Lipid Nanoparticles with Interpretable Machine Learning

Mehradfar, Asal et al.
arXiv (All) · Papers
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and-sciencecomputational-engineeringfinancemachine-learningquantitative-methods
Lipid nanoparticles (LNPs) have transformed RNA medicine, yet their clinical utility remains constrained by predominant hepatic accumulation after systemic administration. Redirecting LNPs to extrahepatic tissues requires understanding of how lipid chemistry and formulation composition jointly gover
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