Europe PMC
open access
Tumour hypoxia in clinical oncology: imaging, therapeutic strategies, and translational challenges
Hypoxia, a defining feature of many solid tumours, arises from rapid cellular proliferation, abnormal tumour stroma, and aberrant vasculature. Reduced oxygen availability contributes to several cancer hallmarks, including sustained proliferative signalling, angiogenesis, metabolic reprogramming, imm
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