Universität Innsbruck
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CC BY-SA 4.0
Effect of curcuminoids on 5-lipoxygenase product formation in activated neutrophils
Human polymorphonuclear leukocytes (PMNL) were pre-treated with DMSO or curcuminoids, 5-LOX product formation was initiated by arachidonic acid (AA, 20 µM) and A23187 (2.5 µM) and 5-LOX products (LTB4, its isomers et-LTB4, t-LTB4, and 5-H(p)ETE) were analyzed by RP-UV-HPLC. &
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