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Checkpoint Deficient Rad53-11 Yeast Cannot Accumulate Dntps in Response To Dna Damage
Deoxyribonucleotide pools are maintained at levels that support efficient and yet accurate DNA replication and repair. Rad53 is part of a protein kinase regulatory cascade that, conceptually, promotes dNTP accumulation in four ways: (1) it activates the transcription of ribonucleotide reductase subu
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