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FMISO-based Adaptive Radiotherapy for Head and Neck Cancer

University Hospital Olomouc · 2022
ClinicalTrials.gov · Datasets · License: Public Domain · 2022
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head-and-neck-cancerhypoxianaradiotherapy
Hypoxia occurs in about 80% of head and neck tumors. Based on experimental and clinical data, hypoxia is a useful parameter for pretherapeutic stratification. These radioresistant regions can be detected with FMISO PET/CT. Moreover, hypoxic subvolumes of tumors can be evolving as target volumes for radiotherapy ("dose painting") in hypoxia imaging-based dose escalation.
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