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Oral tolerance induced by ovalbumin modulates the cytokine profile and increases the frequency of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs expressing the GARP/LAP late-stage activation markers in antigen-stimulated cells of <i>P.paulista</i> wasp venom-sensitized mice

Luís Gustavo Romani Fernandes (25088240) et al.
Figshare · Datasets · License: CC BY 4.0
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biotechnologycancercell-biologyimmunologyinfectious-diseasesspace-science
Venom immunotherapy (VIT) successfully modulates immune responses to venom allergens. However, it may fail in multisensitized patients and cause severe adverse reactions. Bystander suppression mechanisms could enhance VIT efficacy by creating a tolerogenic microenvironment that induces modulatory
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