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IL-1β drives SARS-CoV-2-induced disease independently of the inflammasome and pyroptosis signalling

Stefanie M. Bader (24471083) et al.
Figshare · Datasets · License: CC BY 4.0
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biochemistry-and-cell-biologybiodefensebiological-sciencesbiomedical-and-clinical-sciencescoronaviruseshealth-scienceslung
Excessive inflammation and cytokine release are hallmarks of severe COVID-19. Certain programmed cell death processes can drive inflammation, however, their role in the pathogenesis of severe COVID-19 is unclear. Pyroptosis is a pro-inflammatory form of regulated cell death initiated by
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