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Measurements of cell viability, colony formation, apoptosis, DNA damage, gene expression and promoter occupancy in head and neck squamous cell carcinoma cells treated with histone lysine demethylase inhibitors and panobinostat
Context: Head and neck squamous cell carcinoma (HNSCC) has unsatisfactory clinical outcomes, particularly in advanced disease, and epigenetic drugs are being investigated as a way to improve treatment. Histone deacetylase inhibitors such as panobinostat have shown limited efficac
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