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Use of luminescent proximity-based techniques to investigate IL-23 receptor complex formation, cytokine binding and activation in living cells
The cytokine IL-23 is a pro-inflammatory messenger molecule, involved in upregulating the immune response after infection by fungal and bacterial pathogens. The pathway is also crucial to the induction and maintenance of several auto-inflammatory diseases, including Psoriatic Arthritis, Plaque Psori
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