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Treatment of Diabetes in Patients With Systolic Heart Failure

Virginia Commonwealth University · 2016
ClinicalTrials.gov · Datasets · License: Public Domain · 2016
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diabetes-mellitusheart-failuresystolictype-2type-2-diabetes
Investigator Initiated Study to study the effects of Canagliflozin 100 milligrams (mg) vs Sitagliptin 100 mg on parameters of aerobic exercise capacity (peak oxygen consumption \[VO2\]) and ventilator efficiency (minute ventilation \[VE\]/carbon dioxide production \[VCO2\] slope) at cardiopulmonary exercise test (CPET) after 12 weeks of active treatment (primary endpoints). Blood pressure (BP), body water content, body composition, cardiac function, and diet will be also measured (secondary endpoints).
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