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Determine PK Profiles of Ozanimod and Its' Major Metabolites in Healthy Subjects

Corium Innovations, Inc. · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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multiple-sclerosispharmacokineticsulcerative-colitis
The goal of this clinical trial is to learn how Ozanimod drug can be administered to the healthy subjects via transdermal delivery system (TDS, patch) to achieve better drug absorption and delivery than via oral capsules (Zeposia). Researchers will compare two administered routes of Ozanimod TDS and oral Zeposia in drug pharmacokinetics, tolerability and safety. Participants will either take one capsule only or wear a patch on his/her arm for 7 days, and blood samples will be collected to measure drug concentrations and local skin reactions will be also observed.
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