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Ketamine and Levetiracetam as Second-line Antiseizure Medication for Status Epilepticus in Children

Sohag University · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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About 40% of children with generalized convulsive status epilepticus (GCSE) are not terminated by first-line benzodiazepines (BDZs), and approximately 50% of BDZ-refractory GCSE are not controlled by second-line antiseizure medications. This study investigates the efficacy of ketamine-levetiracetam combination vs. levetiracetam alone for treating children with BDZ-refractory GCSE.
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