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High-throughput screening system for antimycobacterial compounds using in vitro infected cells: construction and application to compounds in the Ōmura Natural Compound Library

Takii, Takemasa et al.
OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY · Papers
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mycobacterium-tuberculosis
The global increase in multidrug-resistant tuberculosis strains poses a major threat; consequently, there is an urgent need to identify and develop novel drugs. We have previously presented a simple fibroblast assay (SFA) screening method that enables the simultaneous assessment of antibacterial act
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