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The kinetoplastid-specific transcription factor mtTF1 is essential for mitochondrial gene expression and maxicircle replication in <i>Trypanosoma brucei</i>

Bianca Manuela Berger et al.
PLOS · Papers · License: CC BY 4.0
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mitochondriamitochondrial-dnarna-interferencetranscription-factors
Mitochondrial DNA replication and gene expression are essential for cell survival. In Trypanosoma brucei, a protozoan animal and human parasite, the mitochondrial RNA polymerase (mtRNAP, Tb927.11.5780) plays roles in both transcription and DNA replication. This study identifies and characterizes th
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