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Selective Microglial Depletion Using an Inducible Tmem119 Mouse Model

Kang, Rachel et al.
ScholarlyCommons at Penn · Papers
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microglianeuroscience-and-neurobiology
Microglia are specialized immune cells of the central nervous system and promising therapeutic targets for neurological disease. However, commonly used genetic approaches can also target other myeloid populations. We evaluated an inducible Tmem119CreERT2 mouse model for selective microglial depletio
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