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Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

International Maternal Pediatric Adolescent AIDS Clinical Trials Group · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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pregnancysyphilis
IMPAACT 2044 is a study to characterize the pharmacokinetics (PK) and safety of ceftriaxone and benzathine penicillin G during pregnancy. Up to 78 pregnant women receiving (1) ceftriaxone for indications other than syphilis or (2) benzathine penicillin G for treatment of syphilis from non-study clinical care providers will be enrolled at study sites located in the United States. Approximately 22 infants of pregnant participants receiving benzathine penicillin G will also be enrolled.
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