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Effects of Pravastatin on Cholesterol, Inflammation and Cognition in Schizophrenia

Massachusetts General Hospital · 2010
ClinicalTrials.gov · Datasets · License: Public Domain · 2010
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cholesterolcognitioninflammationschizophrenia
This study involves people with schizophrenia or schizoaffective disorder, who are currently taking antipsychotic medications. Some antipsychotic medications may cause an increase in cholesterol levels, which may lead to inflammation in the body. Inflammation poses a risk in developing heart disease, diabetes and problems with brain function. The purpose of this study is to see if pravastatin can: * Lower cholesterol * Decrease inflammation * Improve cognition in patients with schizophrenia
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