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Phase I Study of Olaparib With Cisplatin Based Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

University College, London
ClinicalTrials.gov · Datasets · License: Public Domain
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biomarkerscarcinomachemoradiotherapycisplatingenetic-markerspharmacokineticsradiotherapy
The aim of this study is to find the safe dose and best dosing schedule of olaparib to give in combination with cisplatin based chemoradiotherapy (CRT) in patients with locally advanced head and neck cancer. The dose decided on in this part of the study will become the recommended dose for the randomised Phase II trial.
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