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An Efficacy and Safety Study of Lanabecestat (LY3314814) in Early Alzheimer's Disease

AstraZeneca · 2014
ClinicalTrials.gov · Datasets · License: Public Domain · 2014
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alzheimer-s-diseasedeliriumdementiamental-disorders
The purpose of this study is to assess the efficacy and safety of lanabecestat compared with placebo administered for 104 weeks in the treatment of early Alzheimer´s disease. The study will test the hypothesis that lanabecestat is a disease-modifying treatment for participants with early Alzheimer´s disease, defined as the continuum of participants with mild cognitive impairment (MCI) due to Alzheimer´s disease and participants diagnosed with mild dementia of the Alzheimer´s type, as measured by change from baseline on the 13-item Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog13) score at week 104 in each of the 2 lanabecestat treatment groups compared with placebo.
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