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Exploring Fructose Mimetics as Chemotherapeutic Potentiators: Impact on GLUT5-Mediated Cancer Cell Vulnerability
Metabolic reprogramming toward increased sugar uptake is a hallmark of cancer, and fructose-specific uptake through the facilitative transporter GLUT5 is selectively upregulated in several adenocarcinomas, including breast and lung cancer. This dissertation develops and characterizes a panel of fluo
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