Whole-skull acoustic transparency from a single time-reversal solve for reciprocity-based transducer placement and aperture optimization in transcranial focused ultrasound

Transcranial focused ultrasound is limited by the skull, whose thickness, density and curvature aberrate and attenuate the beam in a position- and target-dependent way, making the choice of where to couple a transducer for a given deep target a central planning problem. This work shows that a single