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A rate equation approach to elucidate the kinetics and robustness of the TGF-beta pathway

Melke, Pontus et al.
Lund University Publications · Papers
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biophysics
We present a rate equation model for the TGF-beta pathway in endothelial cells together with novel measurements. This pathway plays a prominent role in inter- and intracellular communication and subversion can lead to cancer, fibrosis vascular disorders, and immune diseases. The model successfully d
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