PLOS
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CC BY 4.0
The parental intestinal microbiome modulates systemic and local glucocorticoid levels in neonatal mice
Glucocorticoids (GCs) are steroid hormones predominately produced by the adrenal glands and secreted into the blood, but are also produced locally within some target tissues. During early development in mice, postnatal day (PND) 2–12, local GC levels in lymphoid organs are higher than blood GC leve
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