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Microwave Therapy for Treatment of Precancerous Actinic Keratoses
This is a two-stage feasibility study to determine if focussed microwave energy is a suitable treatment for Actinic Keratoses (AK). The two study stages are as follows: Stage 1: To determine the electrical properties of permittivity in AK on the hand and bald scalp for subsequent optimisation of the SWIFT instrument to provide the correct dose of microwave energy to the AK. Stage 2: 1. Evaluate the efficacy of microwave energy as a treatment for AK 2. Evaluate the long-term resolution of AK following microwave treatment 3. Assess the feasibility and acceptability of using microwave energy as a treatment for AK 4. Identify the potential mode of action of microwave energy in the treatment of AK. The primary objective is to evaluate the efficacy of microwave therapy versus no treatment on the resolution of AK lesions using visual assessment. The primary outcome measure is full or partial resolution of the AK assessed by skin examination.
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