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TopoFuse: Topology-Aware Tri-Planar Fusion for 3D Cryo-Electron Tomography Segmentation
Automated segmentation of cryo-electron tomograms routinely produces masks that are voxel-accurate but topologically broken: membranes fragment, organelles merge into one another, and enclosed cavities collapse. Existing topology-aware losses reduce these violations but cannot eliminate them, becaus
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