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Mathematical Modelling of Within-Host HIV Dynamics with Cytotoxic Immune Response and Antiretroviral Therapy

Polyakov, Maxim et al.
arXiv (All) · Papers
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medical-physicspopulations-and-evolutionquantitative-methods
We develop and analyse a mechanistic ODE model of within-host HIV dynamics that includes uninfected CD4$^+$ T cells, latently and productively infected cells, free virions, and cytotoxic immune effectors. Antiretroviral therapy is described by two time-dependent efficacy functions that separately re
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