Dosimetric equivalence of deep learning prostate contours after LDR brachytherapy: pre-declared margins, patient-level acceptance thresholds and the incremental predictive value of DVH indices

Background and purpose: Dose Volume Histogram (DVH) indices remain the main dose-effect metrics for toxicity prediction, but they depend on how contours were made. Inter-observer variability (IOV) is unavoidable and clinically accepted, so the question for automatic segmentation addresses equivalenc