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Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study

Odense University Hospital · 2014
ClinicalTrials.gov · Datasets · License: Public Domain · 2014
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ulcerative-colitis
Clinical experience show limited effect of the drug Loperamide used to decrease output in stoma patients. Therefore the investigators see the need for a randomized blinded clinical trial to determine the effect of Loperamide opposite Placebo. Loperamide will be evaluated in relation to the following parameters * Change in ileostomy output in g/day in relation to oral intake * Quantification of the change in intestinal transit time using a radiopaque marker * The patient´s own assessment on which period they received Loperamide or Placebo
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