Dipòsit Digital de la Universitat de Barcelona
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Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells
Survival for lung cancer patients remains dismal and is largely attributed to treatment resistance. To identify novel target genes the modulation of which could modify platinum resistance, we performed a high-throughput RNAi screen and identified Yes-associated protein (YAP1), a transcription coacti
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