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A hERG blocker facilitates K+ channel current by promoting pore opening while blocking

Docken, Steffen S et al.
eScholarship · Papers
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Many drugs that block voltage-gated K+ channels encoded by the human ether-à-go-go-related gene (hERG) can cause long QT syndrome and life-threatening cardiac arrhythmias, yet the molecular mechanisms that determine this risk remain unclear. A process that may counteract arrhythmogenic hERG block, t
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