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Asparagine and glutamine ladders promote cross-species prion conversion

Kurt, Timothy D et al.
eScholarship · Papers
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Prion transmission between species is governed in part by primary sequence similarity between the infectious prion aggregate, PrPSc, and the cellular prion protein of the host, PrPC A puzzling feature of prion formation is that certain PrPC sequences, such as that of bank vole, can be converted by a
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