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Afadin orients cell division to position the tubule lumen in developing renal tubules

Gao, Lei et al.
eScholarship · Papers
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31-biological-sciences-for-2020
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found that the F-actin-binding protein afadin is required for lumen continuity in developing renal tubules, though its mechanism of action r
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