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Sex-specific mitochondrial dysregulation and metformin response in Wilson disease

Medici, Valentina et al.
eScholarship · Papers
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31-biological-sciences-for-2020
Wilson disease (WD) is an inherited disorder of copper metabolism characterized by hepatic copper accumulation, mitochondrial injury, and systemic metabolic dysfunction. Metformin is a widely used antihyperglycemic agent with known effects on mitochondrial metabolism and cellular redox state. We tes
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