PLOS
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CC BY 4.0
Tumor microbial biodiversity and microsatellite instability in colorectal cancer
Background: Growing evidence links the gut microbiome to colorectal cancer (CRC) progression, with certain bacterial species enriched in specific molecular tumor subtypes. DNA mismatch repair deficiency in CRC, evidenced by the presence of microsatellite instability (MSI), has been consistently asso
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