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Identifying the Sulfotransferases Responsible for Minoxidil Bioactivation in Human Hair Follicles
Minoxidil is the only FDA-approved topical treatment for hair loss. While its mechanism of action is not yet fully understood, minoxidil must be sulfated by cytosolic sulfotransferases (SULTs) to reach its active form, and SULT1A1 has long been assumed to be the enzyme primarily responsible. However
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