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Copper as a Metalloregulator of CaMKK2: A Novel Mechanism of AMPK Activation in HCC
Calcium/Calmodulin-dependent Protein Kinase Kinase 2 (CaMKK2) is a central neuronal signaling kinase that integrates calcium signals to regulate metabolism, gene expression, and synaptic plasticity, as well as a key up-regulator of mTOR pathways involved in hepatocellular carcinoma growth. Disrupted
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