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GS-441524 for COVID-19 SAD, FE, and MAD Study in Healthy Subjects

National Center for Advancing Translational Sciences (NCATS) · 2024
ClinicalTrials.gov · Datasets · License: Public Domain · 2024
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covid-19
The goal of this clinical trial is to evaluate the safety, tolerability, and pharmacokinetics of GS-441524 in healthy subjects. The main questions to answer are: 1) What dosage of GS-441524 is required for adequate therapeutic plasma levels? 2) Does fed or fasted state produce variability in plasma levels? 3) How is GS-441524 eliminated from the body. Participants will receive varying levels of GS-441524 or placebo to evaluate AEs and plasma levels.
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