African Surgical OutcomeS-2 (ASOS-2) Trial

An international, multicentre, African cluster randomised trial. Primary objective : To determine whether increased postoperative surveillance in high-risk adult surgical patients reduces overall in-hospital mortality in surgical patients aged 18 years and over in Africa. Primary outcome measure: In-hospital mortality, censored at 30 days if the patient is still alive and in-hospital. Secondary objective: To determine whether increased postoperative surveillance in high-risk adult surgical patients reduces the overall incidence of the composite of severe in-hospital complications and mortality in adult surgical patients aged 18 years and over in Africa. Secondary outcome measure: Composite of severe in-hospital complications and mortality, censored at 30 days if the patient is still alive and in-hospital.