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IV Ketorolac on Platelet Function Post-Cesarean Delivery

Beth Israel Deaconess Medical Center · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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analgesiapostpartumpostpartum-hemorrhage
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption. The effect of NSAIDs on healthy volunteers results in inhibition of platelet aggregation and prolonged bleeding time. However, in the obstetric population, the presence and degree of platelet inhibition after NSAID exposure is less clear. The investigators plan to use Platelet Aggregometry and Thromboelastography (TEG) to evaluate the effect of ketorolac on platelets.
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