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Allogeneic ABCB5-positive Stem Cells for Treatment of Acute-on-Chronic Liver Failure

RHEACELL GmbH & Co. KG · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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mesenchymal-stem-cells
This is an interventional, single arm, multicenter, phase I/IIa clinical trial. The study objective is to investigate the efficacy and safety of three i.v. doses of the investigational medicinal product (IMP) allo-APZ2-ACLF for the treatment of acute-on-chronic liver failure (ACLF). The allogeneic IMP allo-APZ2-ACLF contains skin-derived ABCB5-positive mesenchymal stem cells isolated from skin tissue of healthy donors and stored in a donor cell bank.
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