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Evaluation of the Efficacy of Topical Application of Liquid Nitrogen and Ascorbic Acid in Treatment of Gingival Pigmentation

Al-Azhar University · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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ascorbic-acid
Aim of study The present study will be designed to evaluate the clinical and histomorphometric outcomes of using topical liquid nitrogen and topical ascorbic acid in gingival depigmentation. Primary outcome: • Clinical severity and extension of gingival pigmentation. Secondary outcome: • Histologic assessment of the melanin forming cells.
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