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Skull Base and Low Grade Glioma Neurocognitive Magnetic Resonance Imaging (MRI) Study

Abramson Cancer Center at Penn Medicine · 2010
ClinicalTrials.gov · Datasets · License: Public Domain · 2010
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gliomaradiotherapy
The purpose of this study is to: * estimate the degree of memory loss, if any following radiotherapy to the base of skull or brain as measured by standard neurocognitive battery testing. * describe radiotherapy dose-related changes in vascular perfusion, in spectroscopic parameters of neuronal injury and changes in the degree and directionality of tissue water diffusivity (diffusion tensor imaging) as a measure of white axonal injury. * to relate these imaging characteristics to the degree of memory loss.
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