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SPARK Study - Sympathetic Periarterial Radial Block in Healthy Volunteers

Duke University · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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The SPARK Study evaluates changes in peripheral sympathetic vasomotor activity following a targeted, ultrasound-guided periarterial sympathetic block of the distal radial artery in healthy volunteers. Autonomic reactivity will be assessed before and after the block using digit-specific pulse-amplitude index and infrared thermography during standardized cold pressor testing.
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