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cloneRate: fast estimation of single-cell clonal dynamics using coalescent theory

Johnson, Brian et al.
eScholarship · Papers
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3-good-health-and-well-being-sdg31-biological-sciences-for-2020
MOTIVATION: While evolutionary approaches to medicine show promise, measuring evolution itself is difficult due to experimental constraints and the dynamic nature of body systems. In cancer evolution, continuous observation of clonal architecture is impossible, and longitudinal samples from multiple
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